A new spin on the classic CRISPR gene-editing tool can alter the genome’s chemical tags and suppress gene expression for months.
Rare or common, inherited or spontaneous, mutations form the core of autism risk.
The high levels of serotonin seen in the blood of some autistic people have confounded scientists for more than half a century. Despite so little progress, some researchers refuse to give up.
Loss of the gene KMT5B stunts growth in male mice and leads to social difficulties in female mice, a new study suggests.
Atypical patterns of neuronal activity and gene expression in the striatum may characterize autism in girls, according to a new study.
Worms and zebrafish missing both copies of the gene CHD7 have disrupted cellular signaling, a dearth of inhibitory neurons and behavior changes — all of which are reversed by the stimulant drug ephedrine.
Q&A with Sébastien Jacquemont and Clara Moreau: Why brain imaging signatures for autism are so elusive
The field of neuroimaging will need to combine two strategies before it can find patterns of brain activity or structure unique to autism, the researchers say.
An autism-linked mutation could make the brain grow unusually large by prompting cells to express a chemical signal better known for its connection to cancer.
Researchers have uncovered more than 1,200 new protein-protein interactions involving proteins coded for by autism-linked genes.