The new resource is the first to chart human brain development from before birth to 100 years of age.
Spectrum: Autism Research News
Charting the structure and function of the brain’s many circuits may unravel autism’s mysteries.
Animals with different autism-linked mutations share disruptions to the mTOR signaling pathway, pointing to a potential molecular mechanism for the atypical cerebellar development seen in some autistic people.
Having a genetic predisposition to inflammation is linked to structural changes in brain regions implicated in neurodevelopmental conditions.
A new longitudinal study paints a favorable picture of the outcomes for many autistic adults in the city of Yokohama.
Interneurons that fail to propagate electrical signals in mice that model Dravet syndrome may cause the animals, like people with the autism-linked condition, to die suddenly.
The loss of CHD8, a top autism gene, speeds up the production of certain neurons and leads to overgrowth in spheres of cultured brain cells.
Together, the neurons are part of the corticostriatal circuit, which has been implicated in autism.
The animals recall fear more readily if a set of inhibitory neurons in the hippocampus is switched on.
Models trained on datasets that lack racial and ethnic diversity perform less accurately on brain scans from Black Americans than their white counterparts.