A study of a rare form of epilepsy found in Amish groups adds heft to the idea that mTOR — a much-studied hub in a massive network of brain cell proteins — is an important biochemical player in autism.
Spectrum: Autism Research News
Charting the structure and function of the brain’s many circuits may unravel autism’s mysteries.
Mice engineered to carry a well-known risk factor for schizophrenia show disruptions in the connections between two brain regions that coordinate memory and learning. And these disruptions directly cause problems with working memory — the ability to actively hold information and to recall that information to make a decision, according to a study published in Nature.
Microglia, brain cells that provide immune protection to neurons, may influence the onset and course of Rett syndrome, according to a study published in the Journal of Neuroscience.
FMRP, the protein missing in fragile X syndrome, is needed for the birth of new neurons, for regulating the translation of RNA into protein, and for maintaining the structural integrity of spiny neuronal projections, according to several new studies.
Children who have autism and their healthy siblings share patterns of brain activity that are different than those seen in children with no family history of the disorder, according to unpublished research presented at the IMFAR 2010 conference in Philadelphia.
Brain imaging reveals distinct signatures in the language circuits of young toddlers with autism while they sleep, according to unpublished data presented yesterday at the IMFAR 2010 meeting in Philadelphia.