Guoping Feng’s perseverance has proven a boon to the hundreds of neuroscientists who rely on his most celebrated scientific achievement: two dozen mouse strains engineered to have brightly colored brain cells. By creating the first robust mouse model of obsessive-compulsive disorder, Feng has also found a way to study repetitive behaviors, one of the three core characteristics of autism.
Charting the structure and function of the brain’s many circuits may unravel autism’s mysteries.
Astropolis, a dynamic video game, allows for the unprecedented testing of children with autism on a variety of cognitive skills, all at once, without the artificial, boring and anxiety-ridden setup of a typical psychology lab.
Scientists have for the first time found direct evidence that defects in the GABA receptor sometimes give rise to autism, according to research published 24 November in Molecular Psychiatry.
The pupils of children with autism contract more slowly in response to flashes of light than those of their healthy peers, according to findings published in the November issue of the Journal of Autism and Developmental Disorders.
Using new genetic screening technology, a few research groups are finding that a surprisingly large number of children with autism — at least five percent — have an underlying problem with their mitochondria, the energy factories of the cell.
There are clinical, anatomical and genetic overlaps between autism and certain rare developmental disorders of the cerebellum, and these disorders may help scientists understand autism, according to several studies published in the past year.
Studies on younger siblings of children with autism are finding that during tests of sensory or perceptual processing, these baby sibs show abnormally fast brain responses, rather than a delay.
Autism may be the result of faulty wiring that occurs during early brain development, according to two independent studies that looked at the origins of circuit disruption.
Deleting MeCP2, the gene that’s mutated in Rett syndrome, alters both the size and function of neurons in the mouse brain — at least in one brain region, the locus ceruleus — according to a 30 September report in the Journal of Neuroscience.