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The Brain

Charting the structure and function of the brain’s many circuits may unravel autism’s mysteries.

December 2020
Mutated cells in mouse embryos--the mutations are seen in pink
News

Autism genes affect development of neurons and glia

by  /  11 December 2020

Researchers have devised a new way of seeing how gene mutations affect cells during development.

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Cells transporting NCKAP1 protein in and out of nucleus
News

Rare variants tied to neuronal migration, autism traits

by  /  4 December 2020

Many people with mutations in the NCKAP1 gene have autism or autism traits, according to a new study spanning seven countries.

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Brain images color-coded to show structural changes in autism.
News

Gene expression maps reveal origins of brain changes from autism mutations

by  /  4 December 2020

A new study pinpoints the genes and cell types that may underlie the atypical brain structure seen in people with genetic conditions linked to autism.

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Infant in hospital blankets undergoes a hearing test.
News

Infant hearing test might be sound predictor of autism

by  /  3 December 2020

Babies who are later diagnosed with autism have a sluggish brain response to sound on a universal newborn hearing screen.

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November 2020
Brain diagrams showing connectivity within different regions.
News

Gene mutations point to overlaps in brain connectivity for autism, schizophrenia

by  /  30 November 2020

People who have large mutations associated with autism and schizophrenia share atypical patterns of brain connectivity, according to a new study, especially between areas that process sensory information.

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MRIs show changes over time
News

Big brain may mark subtype of autism

by  /  27 November 2020

Autistic boys with large brains in early childhood still have large brains in adolescence, challenging the long-standing idea that brain enlargement in autism is temporary.

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Dilated mouse pupil
News

Mice reveal roots of sensory issues tied to top autism gene

by  /  23 November 2020

Mice with mutations in the autism-linked gene SYNGAP1 have trouble sensing touch, which may stem in part from brain-circuit alterations and dulled alertness.

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Photograph shows young woman and older woman discussing paperwork.
News

‘Theory of mind’ does not fade with age among autistic adults

by  /  13 November 2020

Autistic people’s ability to understand another person’s thinking does not diminish with age, as it does for non-autistic people.

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Donna Werling portrait
Multimedia / Webinars

Webinar: Donna Werling on gene-expression differences in the brains of autistic people

18 November 2020

On 18 November, Donna Werling spoke about gene-expression patterns in the brains of autistic people, with an emphasis on neurobiology and sex differences.

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hands with a red and blue string puzzle.
Opinion / Reviews

Book Review: ‘The Pattern Seekers’ links human invention — past, present and future — to autism traits

by  /  10 November 2020

Simon Baron-Cohen’s new book is essentially a 272-page argument for his hypothesis that all human innovation stems from the ability to discern and manipulate causal patterns.

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