Skip to main content

TOPIC

Treatments

Efforts to ease the symptoms of autism are beginning to ramp up, with promising candidates in various stages of testing.

News
Illustration: microbes clumped together forming the shape of a brain. The microbes are pink, blue, aqua, and red. Set against a dark blue background.

Despite flurry of findings, doubts dog gut microbes’ role in autism

by  /  19 October 2021
The possibility of microbial treatments for autism has inspired a burst of research and nascent clinical trials, but new research suggests these efforts rest on shaky scientific ground.
News
Photo: A nasal spray bottle sprays upwards.

Intranasal oxytocin ineffective for autism in large trial

by  /  13 October 2021
The hormone is no better than placebo at boosting social behavior in autistic children, according to a new study, but it may still benefit a subset of people with the condition.
News
Medicine being drawn out of a vial with a syringe.

Paused Angelman syndrome trial to restart

by  /  7 October 2021
After imposing a pause in November 2020, the U.S. Food and Drug Administration has cleared the way for a clinical trial of a gene therapy for Angelman syndrome.
October 2021
white lab mouse grooming.
News

Cancer drug alters autism-like traits in mice

by  /  5 October 2021

A drug that helps promote gene expression reduces repetitive behaviors and improves memory and sociability in a mouse model of autism.

0 Comments
Closeup photo of a liquid being poured out of a brown bottle.
News

French pharma firms terminate trials of bumetanide for autism

by  /  1 October 2021

Preliminary results suggested the treatment is no better than placebo at reducing the severity of core autism traits.

0 Comments
September 2021
Mother and child playing with small colored blocks on the carpet.
News

Uncertainty clouds test of ‘preemptive’ therapy to ease autism traits

by  /  24 September 2021

Experts question data showing that an experimental therapy that parents deliver to babies with early signs of autism can lessen the intensity of the children’s traits and lower their chances of diagnosis at age 3.

0 Comments
Many people in different areas on a target.
News

Finding a path forward for fragile X drugs

by  /  23 September 2021

The stubborn lack of treatments for fragile X syndrome — a leading cause of inherited intellectual disability and autism — is spurring researchers to revise clinical trial techniques and revisit old drug candidates.

0 Comments
Opinion / Q&A

Q&A with W. David Lohr: Antipsychotics, polypharmacy among autistic preschoolers

by  /  21 September 2021

Hundreds of preschool-aged children in Kentucky began taking antipsychotic medicines in 2012, according to an analysis of Medicaid records. Lohr discusses what it will it take to get them behavioral therapies instead.

0 Comments
Child makes a row of flowers on the ground.
News

Repetitive behaviors wax and wane among autistic youth

by  /  20 September 2021

Some types of restricted and repetitive behaviors become more prevalent among autistic children and teenagers over time, depending on their age and intellectual ability, whereas others decrease.

0 Comments
Illustration of large microscope with spotlight on DNA strand representing focus on basic research leaving families in the twilight waiting room.
Opinion / Viewpoint

Autism research continues to stress basic science over improving interventions

by  /  14 September 2021

For 40 years, the preponderance of autism research has focused on understanding the causes and characteristics of the condition rather than testing assessments or interventions in community settings.

0 Comments
August 2021
Jeremy Veenstra-VanderWeele headshot
Multimedia / Webinars

Webinar: Jeremy Veenstra-VanderWeele on the state of autism drug development

28 September 2021

On 28 September, Jeremy Veenstra-VanderWeele, professor of psychiatry at Columbia University, spoke about goals for developing new drugs for autism — and the barriers researchers may encounter.

0 Comments
News

Drugs boost serotonin, socialization in multiple autism mouse models

by  /  6 August 2021

The finding that MDMA and an experimental serotonin agonist increase sociability across six different model mice suggests that disparate autism-linked mutations converge on the same underlying pathways.

0 Comments
Portrait of the Lane family in Kentucky.
Features / Deep Dive

Moving for autism care

by  /  4 August 2021

Disparities in state services for autism are driving families to relocate. But not everyone can afford to move, and others find that their new home also has faults.

0 Comments